EnteroMend

EnteroMend is Thorne's comprehensive gastrointestinal support formula — a five-ingredient powder combining L-glutamine with four proprietary, clinically validated botanical and fibre complexes to address intestinal mucosal integrity, GI inflammatory response, gut barrier function, and bowel regularity in a single, easy-mixing, great-tasting daily formula.

Each ingredient is selected from the best-evidenced, most bioavailable forms available at a practitioner level — three of which use patented phytosome or enhanced-extract technologies that substantially improve absorption and clinical efficacy over standard equivalents. The formula is NSF Certified for Sport®, meaning every batch is independently tested for banned substance compliance and label accuracy — making it one of the very few gut health formulas trusted by professional athletes and competitive sports programmes worldwide.

L-Glutamine — 2,500mg L-glutamine is the conditionally essential amino acid that serves as the primary fuel source for enterocytes — the epithelial cells lining the small intestinal mucosa. Under normal physiological conditions, the gut consumes more glutamine than any other tissue in the body. During periods of physiological stress (illness, intense exercise, poor diet, dysbiosis, or prolonged inflammation), glutamine demand can exceed endogenous supply, compromising enterocyte energy metabolism and increasing intestinal permeability. Supplemental L-glutamine directly supports enterocyte energy availability, maintains tight junction protein expression, and is one of the most consistently studied nutrients for supporting healthy gut barrier function. At 2,500mg per serve — a clinically appropriate dose — EnteroMend provides meaningful mucosal fuel support with each serving.

Sunfiber® Partially Hydrolyzed Guar Gum (PHGG) — 1,000mg Sunfiber® is a patented partially hydrolyzed guar gum (PHGG) from Taiyo International — a soluble, prebiotic dietary fibre produced by enzymatic hydrolysis of guar beans that is uniquely well-tolerated compared to other fibre supplements. Standard guar gum causes significant gastrointestinal side effects due to its high molecular weight and rapid fermentation rate. Partial hydrolysis dramatically reduces the molecular weight, resulting in a fibre that dissolves easily, is odourless and tasteless, and produces significantly fewer gas and bloating complaints than inulin, FOS, psyllium, or wheat bran at comparable doses. In the colon, PHGG is fermented by gut bacteria to produce short-chain fatty acids — particularly butyrate, the primary fuel source for colonocytes (large intestinal epithelial cells). Adequate butyrate production is essential for colonic mucosal health, healthy gene expression in colonocytes, and the maintenance of colonic barrier integrity. Clinical research has demonstrated Sunfiber's ability to improve bowel regularity in individuals with occasional constipation or diarrhoea, and to support healthy gut flora composition.

DaltonMax 700® Aloe Vera Extract — 250mg (200:1 potency) DaltonMax 700® is a unique, highly concentrated aloe vera inner gel extract from Improve USA — a 200:1 potency extract that provides 50g of fresh inner gel equivalent per 250mg dose. Critically, it is extracted exclusively from the inner gel of Aloe barbadensis leaves using low-heat dehydration that preserves bioactive polysaccharides (acemannans), and it does not contain the outer leaf or latex portions of the aloe plant that are responsible for aloe's laxative effect and potential gastrointestinal irritation. Research has demonstrated aloe vera inner gel's tissue-protective, mucilaginous, and anti-inflammatory properties in gastrointestinal tissue. DaltonMax 700® is solvent-free and standardised for molecular weight, ensuring consistent biological activity — a notable advantage over standard aloe gel powders, which vary considerably in acemannan content and bioactivity.

Meriva® Curcumin Phytosome — 250mg Meriva® is the world's most clinically researched curcumin formulation, developed by Indena S.p.A., Italy. It complexes curcumin extract from Curcuma longa root with phospholipids from sunflower (phosphatidylcholine) to form a phytosome — a structure in which the active compound is embedded within a phospholipid matrix, dramatically enhancing its solubility, stability, and oral bioavailability. Standard curcumin has poor bioavailability due to poor water solubility and rapid hepatic and intestinal metabolism. Multiple pharmacokinetic studies have demonstrated that Meriva® achieves plasma curcumin levels 29-fold higher than equivalent doses of standard curcumin extract. In the gastrointestinal context, curcumin is valued for its well-documented ability to support a healthy mucosal inflammatory response by modulating NF-κB signalling and COX-2 activity, and for its broader antioxidant protection of intestinal epithelial tissue.

Casperome® Indian Frankincense Phytosome — 250mg Casperome® is Indena S.p.A.'s patented Boswellia serrata phytosome — complexing Boswellia oleo-gum-resin with sunflower-derived phospholipids for enhanced absorption. Boswellia serrata (Indian frankincense) has over 2,000 years of documented use in Ayurvedic medicine for gastrointestinal and inflammatory conditions. Its active constituents — boswellic acids, particularly acetyl-11-keto-β-boswellic acid (AKBA) — are potent inhibitors of 5-lipoxygenase (5-LOX), the enzyme that produces pro-inflammatory leukotrienes in the gut mucosa. Pharmacokinetic comparison of Casperome® versus unformulated Boswellia extract has demonstrated 7-fold higher plasma levels of 11-keto-β-boswellic acid and approximately 3-fold higher plasma levels of β-boswellic acid with the phytosome formulation, confirming meaningfully superior bioavailability. Boswellia's activity in supporting a healthy GI inflammatory response has been examined in multiple clinical studies, including in patients with inflammatory bowel conditions.

What Sets This Product Apart

EnteroMend brings together five genuinely premium, clinically distinguished ingredients in a single convenient powder — none of which are commodity forms. Sunfiber® PHGG addresses the prebiotic and butyrate-support dimension that most gut mucosal formulas overlook entirely. DaltonMax 700® provides the most potent, laxative-free aloe extract available. Meriva® and Casperome® represent the gold standard in curcumin and Boswellia absorption respectively, with pharmacokinetic data demonstrating substantial superiority over unformulated botanical equivalents. The L-glutamine dose at 2,500mg per serve is appropriate for mucosal fuel support without the excessive doses associated with adverse effects at very high intakes. The combination addresses gut mucosal health across four complementary mechanisms simultaneously: epithelial fuel supply (L-glutamine), inflammatory response modulation (curcumin + Boswellia phytosomes), mucosal protection and soothing (DaltonMax aloe), and colonic microbiome and butyrate support (Sunfiber® PHGG). NSF Certified for Sport® status provides an additional quality assurance benchmark absent from most gastrointestinal formulas.

Supplement Facts

Serving Size: 1 scoop (5.6g) Servings Per Container: 30

Other Ingredients: Natural flavours, citric acid, stevia leaf extract (rebaudioside A 95%).

Directions for Use

Adults: Mix 1 scoop into at least 150–180ml of water or a beverage of choice, once or twice daily, or as directed by your healthcare practitioner. Stirs easily; no blending required.

Allergen Information

Free from gluten, dairy, soy, eggs, tree nuts, peanuts, and shellfish. Sweetened with stevia (rebaudioside A) only — no sugar, artificial sweeteners, or artificial flavours. Non-GMO. NSF Certified for Sport®.

Cautions: If you are pregnant or breastfeeding, consult your healthcare practitioner before use. Important drug interaction: Curcumin has been shown to reduce the therapeutic efficacy of cyclophosphamide (Cytoxan) in animal studies and may interfere with camptothecin- and irinotecan-based chemotherapy drugs. Do not use this product concurrently with these agents without medical supervision. If you are taking any prescription medication, consult your healthcare practitioner before use. Keep out of reach of children. Store in a cool, dry place, tightly sealed.

Practitioner Note

Recommended by Stephen Roigard, Naturopath & Clinical Nutritionist. EnteroMend is an excellent choice as a daily gut mucosal support formula for a broad range of presentations — intestinal permeability ("leaky gut"), post-antibiotic gut restoration, training-related GI disturbance in athletes, IBS with mucosal irritation, and general gut barrier maintenance in patients with high-stress, inflammatory, or dietary-driven gut compromise. The combination of L-glutamine, Sunfiber® PHGG, and the two phytosomes delivers a genuinely comprehensive multi-mechanism approach that stands well above generic gut health powders. The Meriva® and Casperome® phytosome forms are the clinically meaningful distinguishing features — without phytosome enhancement, oral curcumin and Boswellia achieve negligible systemic levels at these doses. The chemotherapy drug interaction caution (cyclophosphamide, camptothecin, irinotecan) is clinically significant and must be communicated to oncology patients — curcumin's effect on these agents has been demonstrated in pre-clinical models, and the cautionary principle should be applied in clinical practice. The NSF Certified for Sport® status makes this an easy recommendation for competitive athletes who require certified compliance.

This product is a dietary supplement intended to support general health and well-being. It is not intended to diagnose, treat, cure, or prevent any medical condition. This product has not been evaluated by Medsafe. If symptoms persist or worsen, consult a qualified healthcare practitioner.